Name: triggering receptor expressed on myeloid cells 2 |
Aliases: triggering receptor expressed on myeloid cells 2b, Trem2a, triggering receptor expressed on myeloid cells 2c, Trem2b, triggering receptor expressed on myeloid cells 2a, Trem2c |
Description: PHENOTYPE: Mice homozygous for a knock-out allele display enhanced cytokine production by macrophages in response to toll-like receptor agonists. Mice homozygous for a different knock-out allele show reduced microglial cell survival, proliferation and activation and cell cycle arrest at the G1/S checkpoint. [provided by MGI curators] |
Crossreferences: MGI:1913150, UniProtKB:Q3U2Q4, UniProtKB:Q99NH8, NCBI_Gene:83433, ENSEMBL:ENSMUSG00000023992 |
This information is supplied by the AllianceGenome.org API. |
Compared To: | Log2fold: | SEM: | Adjusted p-value: |
---|---|---|---|
EV-GFPneg Tumor Microglia | 0.074 | 0.269 | 1 |
EV-GFPpos Tumor Microglia | 1.004 | 0.269 | 0.00214193 |
Compared To: | Log2fold: | SEM: | Adjusted p-value: |
---|---|---|---|
Control microglia | -0.074 | 0.269 | 1 |
EV-GFPpos Tumor Microglia | 0.93 | 0.269 | 0.01453177 |
Compared To: | Log2fold: | SEM: | Adjusted p-value: |
---|---|---|---|
Control Microglia | -1.004 | 0.269 | 0.00214193 |
EV-GFPneg Tumor Microglia | -0.93 | 0.269 | 0.01453177 |