Trem2 - RNA Expression

 

Trem2 - Gene Information

Name: triggering receptor expressed on myeloid cells 2
Aliases: triggering receptor expressed on myeloid cells 2b, Trem2c, Trem2a, triggering receptor expressed on myeloid cells 2a, triggering receptor expressed on myeloid cells 2c, Trem2b
Description: PHENOTYPE: Mice homozygous for a knock-out allele display enhanced cytokine production by macrophages in response to toll-like receptor agonists. Mice homozygous for a different knock-out allele show reduced microglial cell survival, proliferation and activation and cell cycle arrest at the G1/S checkpoint. [provided by MGI curators]
Crossreferences: MGI:1913150, UniProtKB:Q3U2Q4, UniProtKB:Q99NH8, ENSEMBL:ENSMUSG00000023992, NCBI_Gene:83433
This information is supplied by the AllianceGenome.org API.
 

Trem2 - Differential Expression

Control Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
EV-GFPneg Tumor Microglia 0.074 0.269 1
EV-GFPpos Tumor Microglia 1.004 0.269 0.00214193

EV-GFPneg Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control microglia -0.074 0.269 1
EV-GFPpos Tumor Microglia 0.93 0.269 0.01453177

GFPpos Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control Microglia -1.004 0.269 0.00214193
EV-GFPneg Tumor Microglia -0.93 0.269 0.01453177