| Name: signal transducer and activator of transcription 1 |
| Aliases: AA408197, RIKEN cDNA 2010005J02 gene, expressed sequence AA408197, 2010005J02Rik |
| Description: PHENOTYPE: Homozygotes for targeted null mutations are largely unresponsive to interferon, fail to thrive, are susceptible to viral diseases and cutaneous leishmaniasis, and show excess osteoclastogenesis leading to increased bone mass. [provided by MGI curators] |
| Crossreferences: MGI:103063, UniProtKB:Q9D323, UniProtKB:A0A087WSQ5, UniProtKB:Q8C497, ENSEMBL:ENSMUSG00000026104, UniProtKB:A0A087WRI1, UniProtKB:Q8CFQ1, UniProtKB:A0A087WSP5, NCBI_Gene:20846, UniProtKB:Q3TW11, UniProtKB:Q8C8M3, UniProtKB:P42225, UniProtKB:Q99K94, UniProtKB:Q8C3V4 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| EV-GFPneg Tumor Microglia | -2.222 | 0.356 | 5.69E-8 |
| EV-GFPpos Tumor Microglia | -3.01 | 0.356 | 3.26E-15 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Control microglia | 2.222 | 0.356 | 5.68724419 |
| EV-GFPpos Tumor Microglia | -0.788 | 0.353 | 0.16997519 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Control Microglia | 3.01 | 0.356 | 3.26E-15 |
| EV-GFPneg Tumor Microglia | 0.788 | 0.353 | 0.16997519 |