Name: superoxide dismutase 2, mitochondrial |
Aliases:
MGC:6144,
manganese superoxide dismutase,
Sod-2,
manganese SOD,
MnSOD
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Description: PHENOTYPE: Mutations affect mitochondrial function. Null homozygotes die early with cardiomyopathy, tissue lipid accumulation, neurodegeneration, motor problems and/or metabolic acidosis depending on strain background. Heterozygotes show mitochondria and apoptosis defects with age. Inducible retina-specific conditional KO results in retinal atrophy.
[provided by MGI curators] |
Crossreferences:
MGI:98352,
ENSEMBL:ENSMUSG00000006818,
UniProtKB:Q4FJX9,
UniProtKB:P09671,
UniProtKB:Q3TJA2,
NCBI_Gene:20656,
UniProtKB:A0A3B2WBF0,
UniProtKB:Q3U8W4,
UniProtKB:A0A3B2W479
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This information is supplied by the AllianceGenome.org API. |