| Name: suppressor of cytokine signaling 1 |
| Aliases:
SOCS-1,
Cish1,
JAB,
JAK-binding protein,
JAK2-binding protein,
cytokine inducible SH2-containing protein 1,
Cish7,
STAT-induced STAT inhibitor 1,
SSI-1
|
| Description: PHENOTYPE: Homozygotes for targeted null mutations exhibit retarded growth, hyperresponsiveness to endogenous interferon gamma, hepatitis with fatty degeneration, lymphopenia due to excess apoptosis, monocytic organ infiltration, and lethality by 3 weeks of age. [provided by MGI curators] |
| Crossreferences:
MGI:1354910,
UniProtKB:O35716,
NCBI_Gene:12703,
ENSEMBL:ENSMUSG00000038037
|
| This information is supplied by the AllianceGenome.org API. |