Ptpn11 - RNA Expression

 

Ptpn11 - Gene Information

Name: protein tyrosine phosphatase, non-receptor type 11
Aliases: AW536184, SH2 domain-containing protein tyrosine phosphatase-2, RIKEN cDNA 2700084A17 gene, 2700084A17Rik, SHP-2, Shp2, Syp, PTP2C, expressed sequence AW536184, SH-PTP2, PTP1D
Description: PHENOTYPE: Homozygous null mutants exhibit abnormal mesoderm patterning leading to a failure of gastrulation and death by embryonic day 10.5. In heterozygous state the null mutant acts as a dominant enhancer of a mild epidermal growth factor receptor mutation. Conditional KO in the eye results in severe retinal degeneration. [provided by MGI curators]
Crossreferences: MGI:99511, UniProtKB:Q05C78, ENSEMBL:ENSMUSG00000043733, NCBI_Gene:19247, UniProtKB:P35235, UniProtKB:Q63848, UniProtKB:Q9CT18
This information is supplied by the AllianceGenome.org API.
 

Ptpn11 - Differential Expression

Control Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
EV-GFPneg Tumor Microglia 0.578 0.374 1
EV-GFPpos Tumor Microglia 0.402 0.373 0.51637376

EV-GFPneg Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control microglia -0.578 0.374 1
EV-GFPpos Tumor Microglia -0.177 0.374 0.84753382

GFPpos Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control Microglia -0.402 0.373 0.51637376
EV-GFPneg Tumor Microglia 0.177 0.374 0.84753382