|Name: protein tyrosine phosphatase, non-receptor type 11
SH2 domain-containing protein tyrosine phosphatase-2,
RIKEN cDNA 2700084A17 gene,
expressed sequence AW536184,
| Description: PHENOTYPE: Homozygous null mutants exhibit abnormal mesoderm patterning leading to a failure of gastrulation and death by embryonic day 10.5. In heterozygous state the null mutant acts as a dominant enhancer of a mild epidermal growth factor receptor mutation. Conditional KO in the eye results in severe retinal degeneration. [provided by MGI curators]
|This information is supplied by the AllianceGenome.org API.