Name: protein tyrosine phosphatase, non-receptor type 11 |
Aliases:
PTP2C,
SH-PTP2,
Syp,
AW536184,
SH2 domain-containing protein tyrosine phosphatase-2,
expressed sequence AW536184,
PTP1D,
2700084A17Rik,
SHP-2,
Shp2,
RIKEN cDNA 2700084A17 gene
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Description: PHENOTYPE: Homozygous null mutants exhibit abnormal mesoderm patterning leading to a failure of gastrulation and death by embryonic day 10.5. In heterozygous state, the null mutant acts as a dominant enhancer of a mild epidermal growth factor receptor mutation. Conditional KO in the eye results in severe retinal degeneration. [provided by MGI curators] |
Crossreferences:
MGI:99511,
ENSEMBL:ENSMUSG00000043733,
UniProtKB:Q05C78,
NCBI_Gene:19247,
UniProtKB:Q63848,
UniProtKB:P35235,
UniProtKB:Q9CT18
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This information is supplied by the AllianceGenome.org API. |