Map3k8 - RNA Expression

 

Map3k8 - Gene Information

Name: mitogen-activated protein kinase kinase kinase 8
Aliases: c-COT, tumor progression locus 2, Cot, Tpl2, Cot/Tpl2, Tpl-2, cancer Osaka thyroid, oncogene
Description: PHENOTYPE: Mutant mice resist endotoxic shock. Their MHC II expression is enhanced. Macrophages' TNF-alpha response to viruses and to all TLR ligands is impaired. Macrophage and T-cell secretion of other cytokines in response to various TLR ligands or OVA is aberrant. Anti-OVA Ig classes are abnormally skewed. [provided by MGI curators]
Crossreferences: MGI:1346878, UniProtKB:Q07174, UniProtKB:Q3U086, NCBI_Gene:26410, UniProtKB:Q3T9M0, UniProtKB:Q3UEB8, UniProtKB:G3UWY2, ENSEMBL:ENSMUSG00000024235
This information is supplied by the AllianceGenome.org API.
 

Map3k8 - Differential Expression

Control Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
EV-GFPneg Tumor Microglia -0.204 0.446 1
EV-GFPpos Tumor Microglia -0.119 0.446 0.90003353

EV-GFPneg Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control microglia 0.204 0.446 1
EV-GFPpos Tumor Microglia 0.085 0.445 0.94264463

GFPpos Tumor Microglia

Compared To: Log2fold: SEM: Adjusted p-value:
Control Microglia 0.119 0.446 0.90003353
EV-GFPneg Tumor Microglia -0.085 0.445 0.94264463