| Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
| Aliases: INVG34, Ia-associated invariant chain, Ii, CLIP |
| Description: PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired transport of MHC class II molecules, poor antigen presentation, and deficiency of CD4+ T cell development and positive selection. [provided by MGI curators] |
| Crossreferences: MGI:96534, UniProtKB:P04441, UniProtKB:Q545Y5, NCBI_Gene:16149, ENSEMBL:ENSMUSG00000024610, UniProtKB:Q3U4Q8 |
| This information is supplied by the AllianceGenome.org API. |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| EV-GFPneg Tumor Microglia | -5.351 | 0.283 | <= 1.0E-32 |
| EV-GFPpos Tumor Microglia | -5.924 | 0.283 | <= 1.0E-32 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Control microglia | 5.351 | 0.283 | <= 1.0E-32 |
| EV-GFPpos Tumor Microglia | -0.573 | 0.282 | 0.22234385 |
| Compared To: | Log2fold: | SEM: | Adjusted p-value: |
|---|---|---|---|
| Control Microglia | 5.924 | 0.283 | <= 1.0E-32 |
| EV-GFPneg Tumor Microglia | 0.573 | 0.282 | 0.22234385 |